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Jun 10, 2026

Top 20 Single-Use Bioreactors Companies: Who's Leading the Next Wave of Growth?

By Transpire Insight


top-20-single-use-bioreactors-companies

Single-use bioreactors are a new and evolving market in biopharmaceutical production. Single-use bioreactors are made of disposable materials, are highly flexible, require very few cleaning steps, and turn over quickly.

Sartorius AG, Danaher Corporation, Eppendorf SE, Getinge ABEC, Inc., and DelveInsight are the prominent companies. The partnership in co-development solutions with biopharmaceutical companies, contract manufacturers, and research institutes is close-knit among the tool manufacturers.

The following blog highlights the list of the top 20 companies in the single-use bioreactors market across the globe.

 

Leading Single-Use Bioreactors Market In The World 

The 10 companies below dominate the single-use bioreactors market in the world. With growing investments in biologics and biosimilars, single-use bioreactors are set to become the industry standard in modern bioprocessing.

  • Sartorius AG

Global leader in bioprocess solutions and one of the strongest innovators in single-use bioreactor technology.

Founded: 1870 | HQ: Gottingen, Germany

Why It Ranks: Sartorius dominates the single-use bioreactors market through advanced bioprocessing systems, scalable disposable technologies, and strong partnerships with biologics manufacturers worldwide. Its systems are widely adopted for vaccine, cell therapy, and monoclonal antibody production.

Regional Dominance: Europe remains Sartorius’ core market, though North America and Asia-Pacific continue driving strong biopharmaceutical demand.

Product Line: Single-use bioreactors, cell culture systems, filtration technologies, bioprocess bags, and upstream biomanufacturing solutions.

Recent Development: In March 2026, Sartorius expanded its single-use bioprocess manufacturing capacity to support growing global biologics production demand.

  • Thermo Fisher Scientific Inc.

One of the world’s largest life sciences companies with strong single-use bioprocessing capabilities
Founded: 2006 | HQ: Massachusetts, USA

Why It Ranks: Thermo Fisher has built a powerful position through integrated bioprocessing platforms, advanced single-use technologies, and global CDMO services supporting biologics manufacturing.

Regional Dominance: North America leads operations, while Europe and Asia-Pacific remain major expansion regions for biologics manufacturing.

Product Line: single-use bioreactors, cell culture media, bioprocess containers, laboratory instruments, and biologics manufacturing systems.

Recent Development: In February 2026, Thermo Fisher expanded bioprocessing manufacturing operations to strengthen single-use technology supply for biologics companies. 

  • Danaher Corporation

Major life sciences company driving innovation in single-use bioprocessing and biologics manufacturing. 

Founded: 1984 | HQ: Washington, USA

Why It Ranks: Through Cytiva and Pall Corporation, Danaher has become a dominant supplier of disposable bioprocess systems for large-scale biologics production.

Regional Dominance: North America remains the company’s strongest market, supported by strong European and Asia-Pacific pharmaceutical operations.

Product Line: Single-use bioreactors, filtration systems, chromatography technologies, cell culture solutions, and bioprocess consumables.

Recent Development: In April 2026, Cytiva expanded its single-use manufacturing systems portfolio to improve biologics production flexibility and scalability.

  • Merck KGaA

Global science and technology company supporting advanced bioprocessing and disposable bioreactor systems

Founded: 1668 | HQ: Darmstadt, Germany

Why It Ranks: Merck KGaA plays a major role in single-use bioprocessing through high-performance cell culture systems and integrated biologics manufacturing technologies.

Regional Dominance: Europe remains the company’s strongest market, though North America and Asia-Pacific continue showing rapid biologics growth.

Product Line: Single-use bioreactors, filtration systems, cell culture media, process monitoring technologies, and bioprocess consumables.

Recent Development: In May 2026, Merck KGaA expanded its single-use bioprocessing solutions portfolio for next-generation biologics manufacturing facilities.

  • Eppendorf SE

Leading biotechnology equipment manufacturer known for advanced laboratory and bioprocess solutions.
Founded: 1945 | HQ: Hamburg, Germany

Why It Ranks: Eppendorf continues strengthening its market position through flexible small-scale and pilot-scale single-use bioreactor systems designed for research and biopharmaceutical development.

Regional Dominance: Europe dominates operations, while North America and Asia-Pacific research laboratories continue driving adoption.

Product Line: Single-use bioreactors, fermenters, laboratory instruments, cell culture systems, and process control technologies.

Recent Development: In January 2026, Eppendorf launched upgraded bioreactor automation features for improved cell culture process monitoring and efficiency. 

  • Getinge AB Applikon Biotechnology 

Swedish healthcare and biotechnology company expanding advanced bioprocessing technologies.

Founded: 1904 | HQ: Gothenburg, Sweden.

Why It Ranks: Through Applikon Biotechnology, Getinge offers scalable single-use bioreactor systems widely used in biologics and cell culture applications.

Regional Dominance: Europe remains its strongest operational market, with growing adoption across Asia-Pacific biopharmaceutical manufacturing facilities.

Product Line: Single-use bioreactors, bioprocess controllers, fermentation systems, cell culture technologies, and process analytics solutions.

Recent Development: In March 2026, Getinge expanded its Applikon bioprocess portfolio with upgraded disposable bioreactor solutions for biologics manufacturers. 

  • ABEC. Inc

Specialized biopharmaceutical manufacturing company focused on large-scale single-use technologies.

Founded: 1974 | HQ: Pennsylvania, USA

Why It Ranks: ABEC is recognized for large-volume disposable bioreactor systems and customized biologics manufacturing solutions used by major pharmaceutical companies.

Regional Dominance: North America dominates operations, though the company also supports global biologics facilities across Europe and Asia-Pacific.

Product Line: Single-use bioreactors, integrated bioprocess systems, cell culture technologies, and custom biologics manufacturing equipment.

Recent Development: In April 2026, ABEC expanded production capacity for large-scale disposable bioreactor technologies supporting commercial biologics manufacturing.

  • Avantor Inc

Global supplier of bioprocessing materials and single-use manufacturing technologies.

Founded: 1904 | HQ: Pennsylvania, USA

Why It Ranks: Avantor supports the biopharmaceutical industry through comprehensive single-use solutions and critical manufacturing materials for biologics production.

Regional Dominance: North America leads operations, supported by strong European and Asia-Pacific life sciences demand.

Product Line: Single-use assemblies, bioprocess containers, filtration systems, laboratory chemicals, and manufacturing consumables.

Recent Development: In May 2026, Avantor appointed Jerry Porreca as the new Executive Vice President for Quality and Regulatory.

  • Repligen Corporation

Bioprocessing technology company specializing in biologics manufacturing efficiency solutions

Founded: 1981 | HQ: Massachusetts, USA.

Why It Ranks: Repligen has become a strong player in single-use bioprocessing through innovative filtration, chromatography, and process intensification technologies.

Regional Dominance: North America remains its primary market, while Europe and Asia-Pacific continue seeing rapid biopharma adoption.

Product Line: Single-use bioreactor components, filtration systems, chromatography products, and process analytics technologies.

Recent Development: In May 2026, Repligen announced a new partnership agreement in China to strengthen local manufacturing access and improve competitiveness in the Asia-Pacific bioprocessing market.

  • PBS Biotech, Inc

Innovative biotechnology company focused entirely on single-use bioreactor systems.

Founded: 2006 | HQ: California, USA

Why It Ranks: PBS Biotech stands out for its airlift-based single-use bioreactor technology designed for scalable and low-shear cell culture applications.

Regional Dominance: North America remains the company’s strongest market, while Asia-Pacific biologics manufacturers are increasingly adopting its systems.

Product Line: Single-use bioreactors, cell culture systems, stem cell bioprocessing technologies, and scalable biologics manufacturing solutions.

Recent Development: In December 2025, PBS Biotech unveiled its new MiniPRO multi-parallel Vertical-Wheel bioreactor platform for scalable closed-system cell therapy process development.

 

Top 20 Single-use Bioreactors Market Companies

  • Sartorius AG (Germany)
  • Thermo Fisher Scientific Inc. (USA)
  • Danaher Corporation (Cytiva & Pall Corporation) (USA)
  • Merck KGaA (MilliporeSigma) (Germany)
  • Eppendorf SE (Germany)
  • Getinge AB (Applikon Biotechnology) (Sweden)
  • ABEC, Inc. (USA)
  • Avantor, Inc. (USA)
  • Repligen Corporation (USA)
  • PBS Biotech, Inc. (USA)
  • Meissner Filtration Products, Inc. (USA)
  • Distek, Inc. (USA)
  • Cellexus International Ltd. (UK)
  • Celltainer Biotech B.V. (Netherlands)
  • CerCell ApS (Denmark)
  • Solaris Biotech Solutions S.r.l. (Italy)
  • Entegris, Inc. (USA)
  • Saint-Gobain Life Sciences (France)
  • Corning Incorporated (USA)
  • OmniBRx Biotechnologies (India)

Download Sample Copy of Single-use Bioreactors Market: https://www.transpireinsight.com/request-sample/3077

 

Future Opportunity

Impact on Single-use Bioreactors Market Companies

Expansion of cell and gene therapy manufacturing.

Creates strong demand for flexible, contamination-free, and scalable single-use bioreactor systems.

Integration of AI and automation in bioprocessing. 

Encourages companies to establish regional manufacturing facilities and localized bioprocess solutions.

Rising adoption of modular and continuous bioprocessing facilities.

Increases demand for disposable bioreactors that reduce setup time, cleaning costs, and operational complexity.

 

Conclusion

The Single-Use Bioreactors market is growing rapidly due to the growing volume of biopharmaceutical production, personalized medicine, and the demand for cheaper and contamination-free production methods. Market growth is also being boosted by technological developments and the growth in the use of technology in emerging economies. As investments in bioreactors and biosimilars increase, single-use bioreactors will soon become the new standard for the bioprocessing industry.

About the Authors


Chakradhar Khansole Author TI

Chakradhar Khansole

Chakradhar serves as the Research Director at Transpire Insight, bringing over 8 years of experience in technology, innovation, and strategic market intelligence. He specializes in transforming complex market data into actionable business insights that enable organizations to make informed, growth-oriented decisions. Recognized for his strategic vision and analytical expertise, Chakradhar leads high-impact research initiatives, delivering comprehensive market assessments, competitive intelligence, and forward-looking industry analysis.

Kartik Bhong Author TI

Kartik Bhong

Dr. Kartik bhong serves as the Senior Manager at Transpire Insight, bringing over 6+ years of experience in market research, strategic consulting, and business intelligence, complemented by a Ph.D. in Market Research and Strategic Management. With extensive expertise in primary and secondary research, quantitative and qualitative analysis, and industry forecasting, he has successfully led complex, multi-sector research engagements for global clients.

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